Considering the geographic distribution, the continents with the highest reported cases were North America (45.3%) and South America (27.9%), followed by Europe (19.4%) and Asia (7.3%). ). The countries that most reflected oral lesions, in decreasing order, were the United States, Brazil, Italy, and China 5 . A higher incidence of oral lesions has been shown in men than in women: 78.9% and 21.1% respectively 5 . Matías MD et al. ensures that the traditional male predominance changed in the last two years, seeing itself surpassed by the female.
The average age was 39.5 ± 16 years, with a predominance of the third and fourth decade of life 5 . The most prevalent forms reported were mucous Kenya Phone Number List patches, macules, papules, and nodular executive email list and ulcerative forms 27 . The most frequent locations are shown in Table 3 . Leucci et al. reviewed the oral manifestations of syphilis in the different clinical stages (primary, secondary and tertiary), and found that they were present in 17%, 58% and 25% of the cases, respectively 28 . However, in more current studies the prevalence was 92.5% in the secondary stage and 7.5% in the primary stage, with no oral lesions in the tertiary.
The other hand, S. Leuci et al. found 42% of chancres located on the tongue, 17% on the labial mucosa, 17% on the buccal commissure, 8% on the buccal mucosa, 8% on the palate, and 8% on the vestibular gingiva 28 . In the secondary stage, mucous plaques have been reported as the most predominant clinical manifestation, preferably located on the lips, tongue, buccal mucosa, and palate. Ulcerated lesions, nodular and maculopapular lesions could also be observed 5,25 . According to Carmona M. et al, in this stage papules predominated in 57.8%, followed by ulcers in 36.8% and keratosis in 5.2% 30 . Tertiary oral syphilis has manifested as gumma and atrophic lutic glossitis, and less frequently as syphilitic.
Nodular and maculopapular lesions could also be observed
Re: Nodular and maculopapular lesions could also be observed
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Re: Nodular and maculopapular lesions could also be observed
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Re: Nodular and maculopapular lesions could also be observed
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Re: Nodular and maculopapular lesions could also be observed
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